2009, Khatkar, M S, Tier, Bruce, Hobbs, M, Khatkar, D, Cavanagh, J A L, Crump, Ronald, Moser, G, Raadsma, H W

We genotyped overlapping samples of Australian dairy bulls using three different SNP chips (15k, 25k and 54k). These chips have different but complementary coverage hence increasing the number of animals and the density and coverage of SNPs to 74k in a combined dataset. A combined analysis of the data from these three SNP chips showed a four fold increase in the coverage of the genome by haplotype blocks over bovine hapmap reported previously (Khatkar et al. 2007). An analysis of contiguous runs of homozygosity revealed long stretches (up to 49.39 Mb) of homozygosity on chromosome 1 in many bulls. Distribution of these segments of homozygosity in a sample of bulls is presented. The results for one chromosome are described in detail.