Implementing a Quality Management System (QMS) is important in order for hospitals to deliver high-quality services. Hospitals in Jordan vary greatly in terms of the quality of their services, with some providing high-quality services and others providing low-quality services. This study aimed to explore QMS obstacles in high- and low-performing hospitals in Jordan using the framework of systems and organizational theories. The study employed a Mixed Method-Sequential Exploratory design. In this sequential explanatory design, data collection utilised the strengths of both quantitative and qualitative methods (i.e. mixed method). A set of questionnaire (yielding quantitative data) was used to explore the QMS obstacles and then interviews (yielding qualitative data) were conducted to identify ways to address these obstacles.