As noted in previous chapters and the Living Is for Everyone (LIFE) Framework (2007), people living in regional and remote areas of Australia appear to be more vulnerable to suicide than people living in metropolitan areas. The aim of this chapter was to provide an overview of the suicide prevention initiatives that target rural communities. We will first discuss suicide prevention initiatives for rural population in general, and then focus on two sub-populations within the rural environment that are at particularly high risk of suicide: farmers and Indigenous persons.